Ginger extract was reported to decrease the MDA level in the liver and also restore the activity of antioxidant enzymes including GPx, glutathione reductase (GR), superoxide dismutase (SOD), and CAT and the hepatic content of reduced glutathione when orally administered to rats with streptozotocin-induced diabetes mellitus for 30 days [25]. This evidence concerns the gene GSR and diabetes mellitus.