Our comprehensive pre-clinical studies in AD transgenic mice have shown that electromagnetic waves/fields “disaggregate” small intra-neuronal aggregates/oligomers of two toxic proteins that appear to be at the root causes of AD – Aβ and tau (Arendash et al., 2010, 2012; Dragicevic et al., 2011; Mori and Arendash, 2011; Arendash, 2012, 2016). This evidence concerns the gene MAPT and Alzheimer disease.