Multivariate analysis showed that recurrence time (P = 0.009, hazard ratio [HR]: 0.978, 95% confidence interval [CI:] 0.962–0.995); tumor size (P = 0.001, HR: 1.149, 95% CI: 1.062–1.242); and AFP (> 400 ng/mL) (P < 0.001, HR: 2.465, 95% CI: 1.486–4.089) were prognostic factors after curative treatment. This evidence concerns the gene AFP and neoplasm.