PRTN3 and rheumatoid arthritis: As shown in Fig. 2, no significant differences in drug survival were found between RA patients treated with and without concomitant csDMARDs (p = 0.47), patients naïve to bDMARDs versus previous users of bDMARDs (p = 0.25), or ACPA-positive versus ACPA-negative patients (p = 0.35).