AFP and hepatocellular carcinoma: A multivariate analysis showed that serum AFP ≥ 100 (HR: 3.103, 95% CI 1.029–9.346, p = 0.044) and Alk-P ≥ 100 U/L (HR: 2.638, 95% CI 1.029–6.536, p = 0.036) were the independent factors associated with poor OS for patients with HCC rupture after SR (Supplementary Table S3).