Venkatesh et al.29 took a similar approach using MRE to differentiate between malignant (including HCC, cholangiocarcinoma (CCA), and metastases) or benign (including hemangioma, hepatocellular adenoma, and focal nodular hyperplasia) focal liver lesions, whereas we used it to distinguish between PLC and SLC. This evidence concerns the gene HSPG2 and hepatocellular carcinoma.