Previous studies have shown that inhibition of HDAC6 protects neurons in many neurological disorder models, including Alzheimer’s disease [12], Parkinson’s disease [13, 39], Huntington’s disease [14], amyotrophic lateral sclerosis (ALS) [15], Charcot-Marie-Tooth disease [16, 17], and ischemic stroke [18]. The gene discussed is HDAC6; the disease is early-onset autosomal dominant Alzheimer disease.