TIMP2 and acute kidney injury: For AKI stage 2, 81 of 294 patients (27.6%) had a [TIMP-2] × [IGFBP7] level greater than 2.0 (ng/mL)2/1000 (new stage 2B), and for AKI stage 3, 62 of 180 (34.4%) had a [TIMP-2] × [IGFBP7] level greater than 2.0 (ng/mL)2/1000 (new stage 3B).