ENSG00000290788 and hyperandrogenism: Early human trials of insertion of the CYP21A gene into the genome through adenovirus transfection are underway, offering potential for long term amelioration of cortisol and aldosterone deficiency and relief of hyperandrogenism in patients with the commonest form of CAH, 21-hydroxylase deficiency, the commonest cause of AI young people (https://adrenastx.com/).