With regard to the recurrent ITPN alterations, MCL amplifications, FGFR2 fusions, and PI3KCA mutations were significantly more common in ITPN than in PDAC/IPMN (P < 0.001, Fisher's exact test) (Table 3). Here, FGFR2 is linked to pancreatic intraductal papillary-mucinous neoplasm.