Consistent with VLCFA preference and localization to peroxisomes, it has been shown that FATP4 interacts with fatty acid synthetase and the peroxisomal ATP-binding cassette half-transporter, adrenoleukodystrophy protein (ALDP) whereby its mutations are the primary cause of X-ALD [90]. The gene discussed is ABCD1; the disease is X-linked adrenoleukodystrophy.