Consistent with VLCFA preference and localization to peroxisomes, it has been shown that FATP4 interacts with fatty acid synthetase and the peroxisomal ATP-binding cassette half-transporter, adrenoleukodystrophy protein (ALDP) whereby its mutations are the primary cause of X-ALD [90]. Here, SLC27A4 is linked to X-linked adrenoleukodystrophy.