ALB and gangrene: Third, we lacked data on patients’ nutritional status.Prior studies have demonstrated that lower albumin levels—as a marker fornutritional status—are associated with treatment failure or limb loss.12,41,43,62 Additionally,DFO may occur simultaneously to gangrene, soft tissue infection, or sepsis.Furthermore, because of the small sample size in some subgroups, the power to detectother associations was limited.