IL6 and COVID-19: In the present study, our primary objectives were to (i) globally profile the stability of SARS-CoV-2 proteins and their degradation pathways, (ii) determine whether the stability of SARS-CoV-2 proteins correlates with antibody responses, and (iii) study if virus-specific antibodies are correlated with proinflammatory interleukin 6 (IL-6) levels in COVID-19 patients, which may aid in the development of effective therapeutic and diagnostic approaches.