Furthermore, the inhibition of KDM1A using two potent KDM1A inhibitors, GSK2879552[79] and pargyline[80,81] was found to re-sensitize the same cells to the effect of sorafenib, partly through suppression of the Wnt/b-catenin signalling pathway and through reduction of the population of cancer stem cell-like cells[72]. The gene discussed is KDM1A; the disease is cancer.