Two studies reported lower steady-state and GC-induced GRγ mRNA levels in ALL leukemic blasts of prednisone good responders (PGR) compared to prednisone poor responders (PPR)[73,74], while others showed that GRγ mRNA induction in vivo in childhood ALL patients was more rapid and higher in PGR compared to PPR[75]. Here, TLE5 is linked to acute lymphoblastic leukemia.