Zhang et al. [81] suggested that exosomal lncRNA MALAT-1 was highly expressed in NSCLC patients and was positively associated with lymphatic metastasis and TNM stage, thereby indicating that exosomal MALAT-1 may be a non-invasive biomarker for diagnosis and prognosis of NSCLC. The gene discussed is MALAT1; the disease is non-small cell lung carcinoma.