CTNNB1 and colorectal carcinoma: For example, it has been shown that exosomal transfer of miR-92a-3p to CRC cells activates the WNT/beta-catenin pathway and inhibits mitochondrial apoptosis, and contributes to cell stemness, epithelial-to-mesenchymal transition, metastasis, and resistance to 5-FU/oxaliplatin treatment[72].