Recently, Guo et al.14 found that the expression of pyroptosis proteins, such as NLRP3, caspase-1, and pro-IL-1β was significantly increased in thyroid tissues of HT patients, and the thyroid mRNA level of inflammasomes was positively correlated with the contents of TPO-Ab and Tg-Ab in serum. This evidence concerns the gene IL1B and hematocrit.