CLEC4D and early-onset autosomal dominant Alzheimer disease: And found that Natural killer cell mediated cytotoxicity, Th1, Th2, and Th17 cell differentiation, C-type lectin receptor signaling pathway, NOD-like receptor signaling pathway, MAPK signaling pathway, and some neurodegenerative disease pathway, for example, Huntington's disease and Alzheimer's disease, were enriched in the DECRs (Figure 3B, Supplemental Table S1).