Visfatin has also been detected in tumor tissue or plasma from patients with various types of cancers 8, high levels of visfatin in tissue or plasma are associated with human pancreatic ductal adenocarcinoma 9, breast tumor 10, clear cell renal cell carcinoma (ccRCC) 11 and thyroid malignancy 12. This evidence concerns the gene NAMPT and nonpapillary renal cell carcinoma.