ATP7A and Menkes disease: Owatari et al.[16] reported that copper-transporting P-type ATPase, ATP7A, confers drug resistance to SN-38, irinotecan, paclitaxel, vincristine, doxorubicin, etoposide, and mitoxantrone by ATP7A cDNA-mediated expression in ovarian cells of a Chinese hamster and immortalized fibroblasts from a patient with Menkes disease.