While Adams et al. [28] reported the presence of circulating atypical EpCAM+ macrophages (i.e., circulating cancer-associated macrophage-like cells) in blood of both breast and pancreatic cancer patients following enrichment by blood filtration, we did not find CD45+ EpCAM+ cells in any of the patients here analyzed. Here, PTPRC is linked to familial pancreatic carcinoma.