This speculation is supported by several pieces of evidence, demonstrating a specific elevated expression of ALDH1B1 in colon cancer[55]; ALDH3B1 in lung, breast, ovarian, and colon cancer[56]; ALDH3A1 in lung cancer[57]; and ALDH7A1 in prostate cancer[58]. This evidence concerns the gene ALDH1B1 and colonic neoplasm.