ZNF445 and hydatidiform mole: Pathological variants of zinc finger protein genes such as ZFP57 and ZNF445 and of genes related to the subcortical maternal complex such as NLRP2, NLRP5, NLRP7, and KHDC3L have been identified in cases of multilocus imprinting disturbances (MLIDs) and recurrent hydatidiform moles (RHMs) [22].