To further investigate the biological role of TEAD4 in BLCA cells, we knocked down the expression of TEAD4 in T24 and 5637 cells via LV-shTEAD4 or upregulated the TEAD4 levels in TCCSUP and 5637 cells, respectively, depending on the experimental purpose (Fig. 5B-E). The gene discussed is TEAD4; the disease is bladder transitional cell carcinoma.