We employed a dual Aβ (H31L21)/pTauSer202,Thr205 (Ch40E8) IHC assay to demonstrate pTau-immunoreactive dystrophic neurites associated with Aβ plaques in HIGH AD case controls (neuritic plaque Tau or NP-Tau; Fig. 4d, top panel). Here, MAPT is linked to Alzheimer disease.