Positive correlations between LH and extent of local tissue injury (rs = 0.78, p < 0 0.0001); length of hospitalization and CT (rs = 1.0, p < 0.0001); PT and aPTT (rs = 0.47, p < 0 0.00) were observed in dogs with coagulopathy. Here, PLOD1 is linked to blood coagulation disease.