We researched the relationship between ERBB3 methylation and immune cell infiltration in cervical cancer microenvironment, finding that (Table 2) the abundance of TH1, MDSC, Macrophage, effector memory CD8 T cell, activated CD8 T cell, immature B cell and regulatory T cell have the significant association with methylation of ERBB3 in cervical tumor immune microenvironment (R > 0.6). The gene discussed is CD8A; the disease is uterine cervix neoplasm.