Indeed, if the histopathological phenotypic classification is based on Ki67 immunohistochemical expression, among other parameters, and if risk categorization by Oncotype DX were considered a “gold standard” or good reference, conventional Ki67 assessment would have classified 1 case of luminal A-like BC in the high-risk group, whereas digital evaluation would have classified only luminal B cases as high risk. Here, MKI67 is linked to breast cancer.