Tumor control after adoptive T cell transfer and the response of melanoma to immune checkpoint therapy depend on the IFNγ-inducible chemokines CXCL9/10 to recruit CXCR3-expressing T cells to the tumor bed.32 45 46 CXCL9 and CXCL10 expression also correlate with T cell infiltration and survival in stage-III melanoma patients.47–49 However, little is known about negative regulators of CXCL9/10 expression in cancer. This evidence concerns the gene CXCR3 and neoplasm.