As presented in Figures 4B, ITPR1 expression level was positive correlated with infiltrating levels of B cells (r = 0.308, P = 4.10e-5), CD8+ T cells (r = 0.419, P = 1.14e-8), CD4+ T cells (r= 0.18, P = 1.95e-2), macrophages (r = 0.597, P = 2.14e-30), neutrophils (r = 0.396, P = 8.46e-8) and dendritic cells (r =0.477, P = 4.17e-11), while negatively correlated with tumor purity(r = -0.125, P = 1.04e-1). This evidence concerns the gene CD4 and neoplasm.