Four of the identified genes have an established connection to deafness: EYA4 (Deafness, autosomal dominant 10, DFNA10 [MIM: 601316]), CDH23 (DFNB12 [MIM: 601543]), GJB2 (DFNA3A [MIM 601544] and DFNB1A [MIM: 220290]), and TRIOBP (DFNB28 [MIM: 609823]).43 The gene discussed is TRIOBP; the disease is deafness.