To assess whether RBM10 expression could modulate apoptosis in EGFR-mutant lung cancer, we first assessed cleavage of the apoptotic biomarker poly (ADP-ribose) polymerase (PARP) in H3255 (EGFR L858R/RBM10 WT) and PC-9 (EGFR del19/RBM10 WT) cells. This evidence concerns the gene EGFR and lung cancer.