As several of the DEC targets are also targets of key cancer‐promoting transcription factors (e.g. OCT4, SOX2, NANOG KLF4 and SUZ12), it is plausible that transcriptional regulation at the level of both transcription factors and the ceRNA network is involved in the stem cell‐like rewiring of FIR20 cells. The gene discussed is POU5F1; the disease is cancer.