MLST8 and acute myeloid leukemia: Overall, our data indicate that BP-mediated downregulation of ALKBH5 leads to decreased m6A demethylation of EIF4EBP1 and MLST8 mRNA and, thereby, reduced EIF4EBP1 and MLST8 RNA stability, contributing to inhibition of AML cell proliferation (Fig. 7c).