BDNF and psychiatric disorder: ❑CPM.Primary Outcomes:◆Non-responder FM patients (to CPM): discriminated from responders based on a composite index of a set of frequent FM symptoms + another set of neuroplasticity markers with a 100% sensitivity and a 98% specificity (controlling analgesic use, pain threshold, sleep quality, catastrophizing, BDNF levels, FM impact, and psychiatric disorders).