TGFB1 and autoimmune thyroid disease: The data of GSEA revealed that TGF-β signaling pathway, adherens junction, ubiquitin-mediated proteolysis, Wnt signaling pathway, and oocyte meiosis were enriched in the high-risk group (Figure 3(a)), while some other pathways were enriched in the low-risk group, including arachidonic acid metabolism, autoimmune thyroid disease, systemic lupus erythematosus, glycerophospholipid metabolism, and primary immunodeficiency.