As in non-squamous NSCLC, druggable genetic alterations include EGFR mutations (target of EGFR TKI e.g. Osimertinib, Afatinib), ALK translocations (target of ALK inhibitors e.g. Alectinib, Brigatinib), and ROS1 translocations (target of ROS1 inhibitors e.g. Crizotinib, Entrectinib) further molecular testing was performed. The gene discussed is ALK; the disease is non-small cell lung carcinoma.