NFKB1 and colorectal carcinoma: For example, we found that in CRC, Streptococcus is correlated with the expression of host genes that regulate WNT signalling and the NF-κB pathway, whereas in IBS Streptococcus is correlated with host genes that modulate macrophage inflammatory response, thus suggesting that this gut microbe may perturb distinct host pathways in CRC and IBS.