REST and small cell lung carcinoma: We were particularly intrigued by RNA-seq and ChIP-seq data in SCLC cells showing regulation by REST of the expression of the Dner gene coding for an atypical and poorly studied NOTCH ligand (DNER, Delta/Notch like epidermal growth factor related receptor)45–47 (Supplementary Fig. 8c, d), suggesting a possible regulation of Notch signaling by REST.