We next confirmed that both the ViP signatures are induced in acute KD (at presentation, ≤10 days of illness) compared to convalescent KD (day 289–3240 of Illness) in a large new cohort of consecutive patients (n = 105) who were diagnosed with the disease prior to the onset of the COVID-19 pandemic (Cohort 1; Supplementary Data 1) (Fig. 1d). The gene discussed is VIP; the disease is COVID-19.