SFMBT1 and malignant colon neoplasm: To investigate the function of HMG20A in combination with SFMBT1 in colon cancer in vivo, we studied xenograft tumors derived from HCT-116/5-FU cell transfected with SCR, sh-HMG20A, sh-HMG20A + scr and sh-HMG20A + sh-SFMBT1.