VEGFA and neoplasm: The expression of VEGFA in the tumor and TME is associated with increased tumor microvessel density, invasiveness, metastasis, and worsened patient prognosis (Apte et al., 2019; Butler, Kobayashi, & Rafii, 2010; Ferrara & Adamis, 2016; Jayson, Kerbel, Ellis, & Harris, 2016; Kerbel, 2008).