T2D: N=317,399; insulin (n [%]): 174,569 (55); sulfonylureas (n [%]): 55,710 (17.55); metformin (n [%]): 114,263(36). T1D: N=41,688; insulin (n [%]): 37,279 (89.42); sulfonylureas (n [%]): 1846 (4.43); metformin (n [%]): 5059 (12.14). The gene discussed is INS; the disease is type 1 diabetes mellitus.