NFKB1 and Alzheimer disease: Strikingly, NF-κB binding sites were more strongly enriched in the AD-specific NFKB1 ChIP-seq peaks than in the matched controls in five pairs (S4 Fig and S7 Table (a representative pair is shown in Fig 4B). We defined NFKB1 peaks that were AD-specific and/or control-specific in three or more subject pairs as “consistently AD-specific” and “consistently control-specific” peaks, respectively (S3C and S3D Fig).