MCP-1 (Monocyte Chemoattractant Protein-1)/ CCL2 (Chemokine C-C motif Ligand 2) protein was significantly higher by 113.5 % in AMD plasma compared to normal plasma: P = 0.0081; Normal plasma = 1 ± 0.2085 a.u.; AMD plasma = 2.135 ± 0.3358 a.u. (Figure 5E). This evidence concerns the gene CCL2 and age-related macular degeneration.