IL-4 (Interleukin-4) protein was significantly higher by 118.5 % in AMD plasma compared to normal plasma: P = 0.0317; Normal plasma = 1 ± 0.1770 a.u.; AMD plasma = 2.185 ± 0.4348 a.u. (Figure 5B). The gene discussed is IL4; the disease is age-related macular degeneration.