Treatment with HNG reduced ICAM-1 protein levels by 30.82 % in AMD cells: P = 0.0303; AMD UN CL = 1 ± 0.04168 a.u.; AMD HNG CL = 0.6918 ± 0.09460 a.u. (Figure 2K). Here, ICAM1 is linked to age-related macular degeneration.