IL-13 (Interleukin-13) protein was significantly increased by 336.5 % in AMD plasma compared to normal plasma: P = 0.0043; Normal plasma = 1 ± 0.1707 a.u.; AMD plasma = 4.365 ± 1.076 a.u. (Figure 4E). The gene discussed is IL13; the disease is age-related macular degeneration.