IFN-γ (Interferon-gamma) protein level was significantly higher by 186.1 % in AMD plasma compared to normal plasma: P = 0.0286; Normal plasma = 1 ± 0.1416 a.u.; AMD plasma = 2.861 ± 0.7355 a.u. (Figure 3I). This evidence concerns the gene IFNG and age-related macular degeneration.