Treatment with HNG reduced TNF-α protein levels by 46.09 % in AMD cells: P = 0.0381; AMD UN CL = 1 ± 0.1594 a.u.; AMD HNG CL = 0.5391 ± 0.1198 a.u. (Figure 3C). The gene discussed is TNF; the disease is age-related macular degeneration.