Some of the DEGs in diarrhoea-susceptible sheep, enriched in GO terms and sub-network analysis, included IL-6, LOC101121216 (serum amyloid A), SIGLEC1, CHI3L1, S100A9, CD14, CD68, CD86, Ovar-DRB1, IL1RL1, LOC101103238 (CXCL5), CCL22 and IL1RN. The gene discussed is CHI3L1; the disease is Diarrhea.