CASP3 and non-small cell lung carcinoma: The expression levels of apoptotic proteins including BAK, BAX and Caspase-3 were reduced in cells overexpressed RP11-10A14.5 compared to the control group (Fig. 5G, H); the expression levels of apoptotic proteins including BAK, BAX, and Caspase-3 were increased in RP11-10A14.5 knockdown NSCLC cells, compared to the control group (Fig. 5G, H).