Additionally, the grade II gliomas most often associated with BRAF genetic alterations were pleomorphic xanthoastrocytomas, similar to the findings of Myung et al. (23) Most samples with MYB- PCDHGA1 translocation and MYBL1 genetic rearrangement did not have a BRAF genetic alteration (9). Here, PCDHGA1 is linked to central nervous system cancer.