SELP and deep vein thrombosis: Elevated P-selectin, which mediates platelet endothelial interaction, shows that damage to the venous wall could be the inciting event (Jezovnik and Poredos, 2010).However, other studies found no difference concerning concentration of four major soluble cell adhesion molecules (sCAMS) between patients with DVT and controls in the acute phase (Bucek et al., 2003), which would indicate activation of vascular endothelial cells does not play a central role, at least acutely (Bucek et al., 2003).